We investigated how by-products from Lactobacillus rhamnosus can affect uropathogenic Escherichia coli (UPEC), the bacteria commonly responsible for urinary tract infections (UTIs). Our findings revealed that lactic acid, hydrogen peroxide, and other compounds from these probiotics significantly inhibited the growth of UPEC.
Additionally, they reduced the production of proteins that help the bacteria cling to the urinary tract. This suggests that Lactobacillus rhamnosus and its by-products offer protective benefits against UTIs by combating harmful bacteria and reducing their ability to establish infections.
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Probiotic catheters may prevent CAUTIs3D-Bioprinted Urinary Catheters Enable Sustained Probiotic Recovery Under Flow and Improve Bladder Colonization In Vivo.
Highly relevant to CAUTI prevention
We explored the use of 3D bioprinted catheters to deliver Lactobacillus rhamnosus as a potential preventative measure against catheter-associated urinary tract infections (CAUTIs). In our assessment, the bioprints successfully supported the growth and viability of L. rhamnosus under simulated urine flow conditions. Remarkably, this probiotic managed to colonize the bladder without causing tissue inflammation.
Our findings suggest that these bioprinted probiotic catheters could be a promising new approach to help combat CAUTIs, offering a safe and effective strategy to reduce pathogen colonization in urinary catheters.
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We evaluated the effectiveness of Lactobacillus strains from kefir in preventing urinary tract infections caused by Uropathogenic E. coli (UPEC). This study involved testing twelve different Lactobacillus strains to see how well they could inhibit UPEC biofilm formation and their overall antimicrobial effects.
Interestingly, four of the strains showed a strong ability to inhibit biofilm formation by 62-75%. These results suggest that Lactobacillus may have promising applications in managing urinary tract infections, specifically through its ability to disrupt harmful biofilms.
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We investigated the impact of a probiotic treatment, including Lactobacillus rhamnosus, on preventing urinary tract infections (UTIs) in young children after their first febrile UTI.
In our study, 181 children aged 4 months to 5 years were randomly given either a probiotic mixture or a placebo for 18 months.
The results were promising, showing that the probiotic group had a higher UTI-free survival rate (96.7%) compared to the placebo (83.3%) and experienced a longer median time to recurrence.
Overall, probiotics, including Lactobacillus rhamnosus, seem to offer a beneficial alternative to reduce recurrent UTIs in children.
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We investigated how the probiotic GG could help malnourished children reduce infections and improve their overall well-being. In our study, 50 children received standard nutrition, while another 50 had the same diet plus GG for three months.
As we collected data on infection rates, we found that children taking GG experienced fewer upper respiratory and urinary tract infections. Additionally, this group saw better improvements in body mass index, compared to the control group.
It turns out, regular GG intake can significantly bolster health in malnourished kids.
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